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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CD3EAP All Species: 8.79
Human Site: T249 Identified Species: 38.67
UniProt: O15446 Number Species: 5
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15446 NP_036231.1 510 54986 T249 L G V L F P S T T K K R K K P
Chimpanzee Pan troglodytes XP_001164858 510 54940 T249 L G V L F P S T T K K R K K P
Rhesus Macaque Macaca mulatta XP_001110546 515 55824 T252 L G V L L P S T T K K R K K P
Dog Lupus familis XP_855118 530 57442 K257 K K R K K K P K E A E M V E P
Cat Felis silvestris
Mouse Mus musculus Q76KJ5 399 43064 L168 G P G S A S A L R S P T S G K
Rat Rattus norvegicus NP_001102886 458 49394 A226 H V D E E A E A K G M E P L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 89.9 57.5 N.A. 48.8 51.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 92.2 66.4 N.A. 55.8 59.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 6.6 N.A. 0 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 20 N.A. 6.6 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 17 17 17 17 0 17 0 0 0 0 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 17 17 0 17 0 17 0 17 17 0 17 0 % E
% Phe: 0 0 0 0 34 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 17 50 17 0 0 0 0 0 0 17 0 0 0 17 0 % G
% His: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 17 17 0 17 17 17 0 17 17 50 50 0 50 50 17 % K
% Leu: 50 0 0 50 17 0 0 17 0 0 0 0 0 17 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 17 17 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 17 0 0 0 50 17 0 0 0 17 0 17 0 67 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 17 0 0 0 0 0 17 0 0 50 0 0 0 % R
% Ser: 0 0 0 17 0 17 50 0 0 17 0 0 17 0 0 % S
% Thr: 0 0 0 0 0 0 0 50 50 0 0 17 0 0 0 % T
% Val: 0 17 50 0 0 0 0 0 0 0 0 0 17 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _